Innovation Discovery Grants Program
Mass General Brigham Innovation Discovery Grants Program
MASS GENERAL BRIGHAM INNOVATION DISCOVERY GRANTS PROGRAM - 2021
Background and Purpose
The Innovation Discovery Grants (IDG) program aims to enhance the commercial outcomes of the Mass General Brigham community and increase its innovative potential. It is designed to stimulate new inventive concepts, identify areas of commercially significant scientific strength and accelerate commercialization of Mass General Brigham intellectual assets.
Areas of Interest
In 2021, IDG will focus on Cell and Gene Therapy. For purposes of this RFA, Gene Therapy is defined as a subset of genomic medicine that includes all therapeutic modalities that treat a genetic disorder by influencing the structure, expression or inhibition of a gene and the consequent gene product(s).
Key Dates and Information
Pre-proposals are due no later than January 11th, 2021 11:59pm EST.
Full proposals will be invited by February 22, 2021.
Full proposals will be due March 30th, 2021 11:59pm EST.
Awards will be announced at the World Medical Innovation Forum in May, 2021
The earliest possible start date is June 1st, 2021.
Projects may request up to $100,000 total cost (inclusive of 15% indirect costs).
Project plans must demonstrate tangible outcomes towards commercialization opportunities that improve patient health or healthcare delivery.
Guidelines and further information are available on the opportunity website: https://idg.partners.org/prog/mass_general_brigham_innovation_discovery_grants_idg_/
Intellectual Property
Awards will be governed by the Mass General Brigham Intellectual Property Policy. External pharma and device companies will be actively involved during the review process.
Do not include unprotected proprietary information in your application. Questions related to intellectual property and confidentiality should be directed to your Mass General Brigham Innovation Licensing Manager at 857-307-2400.
Additional information
Questions related to IDG grants policies or procedures should be directed Lesley Watts, Director, B-BIC Operations and Finance at lwatts@partners.org / 857-307-2440. Questions related to the business opportunity should be directed to your Mass General Brigham Innovation Licensing Manager or Market Sector Leader at 857-307-2440.
Innovation Discovery Grants Winners
BH | Brigham and Women's Hospital
MGH | Massachusetts General Hospital
HMS | Harvard Medical School
MEE | Massachusetts Eye and Ear
NWH | Newton-Wellesley Hospital
SRH | Spaulding Rehabilitation Network
2019
Computational and experimental deconvolution of circulating exosomal signals in melanoma immunotherapy patients
Genevieve Boland, MD, PhD
Massachusetts General Hospital
Assistant Professor of Surgery, Surgery, MGH
Embryo assessment and selection using artificial intelligence
Charles Bormann, PhD
Massachusetts General Hospital
IVF Laboratory Director, MGH; Instructor, HMS
A generalizable artificial intelligence platform for brain cancer frozen section diagnosis
Jeffrey Golden, MD
Brigham and Women's Hospital
Chair, Department of Pathology, BH; Ramzi S. Cotran Professor of Pathology, HMS
Making the 'invisible' visible: bringing intimate partner violence into focus
Bharti Khurana, MD
Brigham and Women's Hospital
Director, Emergency Musculoskeletal Radiology, BH; Assistant Professor, HMS
Developing a novel machine learning algorithm to automate drug infusions in the operating room and ICU
Vesela Kovacheva, MD, PhD
Brigham and Women's Hospital
Attending Anesthesiologist, BH; Instructor, Anesthesiology, HMS
Artificial Intelligence Diffraction Analysis (AIDA)
Hakho Lee, PhD
Massachusetts General Hospital
Hostetter MGH Research Scholar, MGH; Associate Professor, Radiology, HMS
Virtual biopsy of brain injury: deep learning to identify diagnostic metabolic biomarkers
Alexander Lin, PhD
Brigham and Women's Hospital
Director, Center for Clinical Spectroscopy, BH; Assistant Professor, Radiology, HMS
Automatic cerebral lesion detection and disease progression in patients with Adrenoleukodystrophy (ALD)
Patricia Musolino, MD, PhD
Massachusetts General Hospital
Co-Director Pediatric Cerebrovascular Service, MGH; Assistant of Neurology, HMS
Disease-specific testing of an artificial intelligence system for tight blood pressure control
Andrew Reisner, MD
Massachusetts General Hospital
Director, Clinical Decision Technology Laboratory, MGH; Associate Professor, Emergency Medicine, HMS
Live pilot test of an artificial intelligence system for trauma care decision-support
Andrew Reisner, MD
Massachusetts General Hospital
Director, Clinical Decision Technology Laboratory, MGH; Associate Professor, Emergency Medicine, HMS
Finding needles in the haystack, using machine learning and natural language processing to identify patients and track disease progression
Li Zhou, MD, PhD
Brigham and Women's Hospital
Associate Professor/Lead Investigator, BH; Associate Professor, HMS
2018
Using deep learning to predict next-day patient discharges to optimize hospital capacity management
Peter Dunn, MD
Massachusetts General Hospital
Vice President, Perioperative Services and Healthcare System Engineering, MGH; Assistant Professor, Anesthesia, HMS
A web-based neural network calculator for ovarian cancer screening using serum miRNA
Kevin Elias, MD
Brigham and Women's Hospital
Director, Gynecologic Oncology Research Laboratory, BH; Assistant Professor, HMS
Machine learning for optimized intraoperative multiplexed quantitative optical image guidance for brain tumor surgery
Alexandra Golby, MD
Brigham and Women's Hospital
Director, Image-Guided Neurosurgery, BH; Professor, Neurosurgery, Radiology, HMS
DeepROP - a point-of-care system for diagnosis of plus disease in retinopathy of prematurity
Jayashree Kalpathy-Cramer, PhD
Massachusetts General Hospital
Director, QTIM Lab, MGH; Associate Professor, Radiology, HMS
Breast cancer scanning initiative: predicting unnecessary surgeries in high-risk-breast lesions
Jochen Lennerz, MD, PhD
Massachusetts General Hospital
Associate Director, Center for Integrated Diagnostics, MGH; Assistant Professor, HMS
Ultrasound-based sensors for physiological monitoring and how they can make MRI and PET/CT scanners work better
Bruno Madore, PhD
Brigham and Women's Hospital
Associate Professor, Radiology, BH, HMS
Augmented digital microscopy for diagnosis of endometrial neoplasia
George Mutter, MD
Brigham and Women's Hospital
Medical Director, Reproductive Endocrinology Laboratory, BH, Professor of Pathology, HMS
Deep-learning facilitated lesion detection in medical images
Jinsong Ouyang, PhD
Massachusetts General Hospital
Physicist, MGH; Associate Professor, HMS
Poly-exposure risk scores for psychiatric disorders
Martin Teicher, MD, PhD
McLean Hospital
Director, Developmental Biopsychiatry Research Program, McLean; Associate Professor, Psychiatry, HMS
Development of a machine learning algorithm-guided approach to treatment selection for depressed patients
Christian Webb, PhD
McLean Hospital
Director, Treatment and Etiology of Depression, Youth Lab, McLean; Assistant Professor, Psychiatry, HMS
Artificial intelligence based seizure detection and classification
Brandon Westover, MD, PhD
Massachusetts General Hospital
Executive Director, Clinical Data Animation Center, MGH; Associate Professor, Neurology, HMS
The identification of intracranial hemorrhage using machine-learning analysis of sparse transcranial ultrasound signals
Philip White, PhD
Brigham and Women's Hospital
Assistant Professor, Radiology, BH, HMS
2016
Scar-free fractional microbiopsy
W. Gerald (Jay) Austen, MD
Massachusetts General Hospital
Edward D. Churchill Distinguished Professor of Surgery, Surgery, MGH
Therapeutic microbiota in food allergy
Lynn Bry, MD, PhD
Brigham and Women's Hospital
Associate Professor of Pathology, Pathology, BH
A noninvasive optical monitoring device system for diagnosis & quantitative monitoring of peripheral artery dysfunction
Blaise Frederick, PhD
McLean Hospital
Associate Professor of Psychiatry, Psychiatry, McLean
Long-acting oxytocin formulation for treatment of obesity
Elizabeth Lawson, MD
Massachusetts General Hospital
Associate Professor of Medicine, Medicine, MGH
Gene therapy platform for the treatment of inherited deafness
Casey Maguire, PhD
Massachusetts General Hospital
Associate Professor of Neurology, Neurology, MGH
Development of long-acting PTH analogs for treatment of hypoparathyroidism
Michael Mannstadt, MD
Massachusetts General Hospital
Associate Professor of Medicine, Medicine, MGH
Granulocyte progenitor transfusions for the treatment of patients with neutropenia
Michael Mansour, MD, PhD
Massachusetts General Hospital
Assistant Professor of Medicine, Medicine, MGH
EveryBaby: wireless heart rate sensor for feedback during newborn resuscitation
Kristian Olson, MD
Massachusetts General Hospital
Associate Professor of Medicine, Medicine, MGH
SMOC2: a novel therapeutic target for kidney fibrosis
Vishal Vaidya, PhD
Brigham and Women's Hospital
Associate Professor of Medicine, Part-time, Medicine, BH
Anti-LAP antibody: a new checkpoint inhibitor for the treatment of cancer
Howard Weiner, MD
Brigham and Women's Hospital
Robert L. Kroc Professor of Neurology, Neurology, BH
2014
Treatment of vein graft disease by suprpressing Dll4-notch signaling
Masanori Aikawa, MD, PhD
Brigham and Women's Hospital
Yoshihiro Miwa Associate Chair and Founding Director, Center for Interdisciplinary Cardiovascular Sciences, BH
Novel approach for prevention of vein graft intimal hyperplasia
W. Gerald (Jay) Austen, MD
Massachusetts General Hospital
Edward D. Churchill Distinguished Professor of Surgery, Surgery, MGH
Knee range of motion monitoring device
Paolo Bonato, PhD
Spaulding Rehabilitation Hospital
Assoicate Professor of Physical Medicine and Rehabilitation, Physical Medicine and Rehabilitation, SRH
Novel treatment for kidney diseases
Joseph Bonventre, MD, PhD
Brigham and Women's Hospital
Samuel A. Levine Distinguished Professor of Medicine, Medicine, BH
Novel non-invasive markers of early inflammation in the kidney
Sylvie Breton, PhD
Massachusetts General Hospital
Professor of Medicine, Emerita, Emeritus, MGH
Noninvasive imaging of fibrinogenesis
Peter Caravan, PhD
Massachusetts General Hospital
Professor of Radiology, Radiology, MGH
Treatment for ovarian cancer
Patricia K. Donahoe, MD
Massachusetts General Hospital
Marshall K Bartlett Distinguished Professor of Surgery, Surgery, MGH
Reducing healthcare utilization in pulmonary embolism
Raul San Jose Estepar, PhD
Brigham and Women's Hospital
Co-Director, Applied Chest Imaging Laboratory, BWH; Associate Professor, Radiology, HMS
Treatment of liver disease with a GLP-a fragment
Joel Habener, MD
Massachusetts General Hospital
Professor of Medicine, Medicine, MGH
Targeting the gut to prevent the metabolic syndrome
Richard Hodin, MD
Massachusetts General Hospital
Professor of Surgery, Surgery, MGH
Rapid diagnostic for infectious diseases
Deborah Tan Hung, MD, PhD
Massachusetts General Hospital
Professor of Genetics, Genetics, MGH; Associate Professor of Medicine, Medicine, BH
Fogarty style balloon-tipped epidural catheter
Ronald Hurley, MD
Brigham and Women's Hospital
Anesthesia, BH
IDG portable magnetic resonance device for the pulmonary ICU
Samuel Patz, PhD
Brigham and Women's Hospital
Professor of Radiology, Radiology, BH
High throughput sequencing to identify novel vaccine antigens
Gerald Pier, PhD
Brigham and Women's Hospital
(Gerald Bryan Pier), Professor of Medicine (Microbiology and Molecular Genetics), Medicine, BH
Sensors for pediatric anesthetic monitoring
Patrick Lee Purdon, PhD
Massachusetts General Hospital
Associate Professor of Anesthesia, Anesthesia, MGH
A device for low field magnetic stimulation
Michael Rohan, PhD
McLean Hospital
Lecturer on Psychiatry, Psychiatry, McLean
Highly accurate freehand volumetric ultrasound device
Anthony Samir, MD
Massachusetts General Hospital
Assistant Professor of Radiology, Radiology, MGH
Nonsurgical alternatives to gastric bypass for treatment of type 2 diabetes
Ali Tavakkoli, MD, MB, BS
Brigham and Women's Hospital
Associate Professor of Surgery, Surgery, BH
Development of hemopexin as prophylaxis for hem-related pathology in premature infants
H. Shaw Warren, MD
Massachusetts General Hospital
Associate Professor of Pediatrics, Pediatrics, MGH
New generation micro dissection for rapid molecular testing
Yukako Yagi, PhD
Massachusetts General Hospital
Research Fellow, Genetics, MGH